Variable-sized welts on the skin - hives and angioedema

Hives is a reactive dermatosis of the skin characterized by the appearance of hives in size and location variables, almost always itchy. Acute hives usually regresses within 24 to 48 hours. If outbreaks continue more than 6 weeks now called chronic hives.

The presence of antigens may or may not produce antibodies. Hence, not all forms of hives have clinical or immunologic mechanism. The mast cell and its mediators are involved in almost all clinical forms but also this process involves neutrophils and lymphocytes.

There is a white dermal wheals surrounded by an erythematous rash that is usually referred to itch. Erythema is due to dilation of blood vessels and the papule to the loss of fluid through these vessels. The rash lasts up to 3 or 4 hours disappear without a trace, if the rash persists for more than 24 hours should be considered in the differential erythema multiform.

In the medical history should inquire about medications you are using, including if you take any supplements or herbs, food intake, the relationship with physical triggers such as heat, cold, sweating. You have to find out about infectious diseases as viral processes, insect bites, inhalant or contact allergens and systemic diseases.

Concerning a number of food allergens are hidden in the diet many similar but may contain different preservatives, preservatives or additives. Antioxidants such as sulfites and metabisulfites meals are used in seafood, vegetables and wines. Tartrazine and tyramine are also involved in the hives.

Acute viral infection may be associated with hives: high respiratory symptoms, hepatitis B. Infectious mononucleosis. Some worms can also trigger hives all ages.

In some chronic hives may be associated with hereditary syndromes such as Muckle-Wells syndrome, protoporphyria erythropoietic inhibitor C3 deficiency, familial cold hives, delayed cold hives, heat hives delayed.

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